FungiHelixSeek-H3

Fine-tuned model of the FungiHelixSeek fungal DNA foundation model for histone mark H3 region prediction (GUE EMP benchmark, S. cerevisiae ChIP-chip).

Property	Value
Task	Binary sequence classification (500 bp windows)
Base model	FungiHelixSeek (470M, MLM)
Dev best accuracy / F1	0.9022
Training	3 epochs, lr 2e-5, single NVIDIA GPU
Dataset	fungi-histone-modifications subset H3

Usage

from transformers import AutoModelForSequenceClassification, AutoTokenizer

model = AutoModelForSequenceClassification.from_pretrained(
    "zhangtaolab/FungiHelixSeek-H3", trust_remote_code=True
)
tokenizer = AutoTokenizer.from_pretrained("zhangtaolab/FungiHelixSeek-H3", trust_remote_code=True)

Dataset

Train/dev/test splits: fungi-histone-modifications (subset H3) · ModelScope

License

CC-BY-NC 4.0 (research use; contact authors for commercial licensing).