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/mnt/sda/filtered tar files/arxiv-8-25/000000515_JSON.tar!000000515/output_0002541/0002541.json | arxiv-old | Learning a model of shape selectivity in V4 cells reveals shape encoding mechanisms in the brain | [{"first": "Paria", "middle": [], "last": "Mehrani", "suffix": "", "affiliation": {"laboratory": "", "institution": "York University", "location": {"settlement": "Toronto", "country": "Canada"}}, "email": ""}, {"first": "John", "middle": ["K"], "last": "Tsotsos", "suffix": "", "affiliation": {"laboratory": "", "institu... | Learning a model of shape selectivity in V4 cells reveals shape encoding mechanisms in the brain | Paria Mehrani (York University); John K Tsotsos (York University) | Computational Neuroscience — Vision | Methodological | This paper introduces SparseShape, a hierarchical model designed to explain shape processing in the ventral visual stream, with a focus on V4. The model addresses two key problems: encoding signed curvature (distinguishing between convex and concave shapes) and part-based selectivity in V4 neurons. SparseShape builds u... | Understanding the transformation of shape signals from early visual areas (V1, V2) to higher-level areas like IT remains a challenge. Existing models of V4 often lack the ability to encode curvature sign, which is crucial for distinguishing between convex and concave shapes. Previous models, such as HMAX and 2DSIL, hav... | The central research questions are how the brain transforms shape signals from early visual areas to V4 and how V4 neurons achieve part-based selectivity. The primary hypothesis is that a hierarchical model, SparseShape, can effectively model the transformation of shape signals, including the encoding of signed curvatu... | The study employed a computational modeling approach, developing and evaluating the SparseShape hierarchical network. The study utilized electrophysiological responses of 109 Macaque V4 neurons reported in [10], which were provided by Dr. Pasupathy. The model was trained and tested on two sets of stimuli: a standard se... | SparseShape is a hierarchical model that combines and extends the 2DSIL and RBO networks. The architecture includes layers representing V1, V2, and V4, with the goal of modeling the transformation of shape signals. The model incorporates edge-and border-selective neurons at 12 orientations in [0, π), combining response... | The SparseShape model demonstrated comparable or improved performance compared to 2DSIL, HMAX, and APC models. The average MAE over all mV4 cells is less than 0.18 in SparseShape versus 0.34 in 2DSIL. The correlation coefficients for the test set were 0.56 for SparseShape and 0.57 for HMAX. The sparsity analysis reveal... | The findings suggest that the ventral stream employs a hierarchical processing approach to shape perception, with signed curvature encoding playing a crucial role. The model's ability to capture both excitatory and inhibitory contributions, as well as long-range interactions between shape parts, provides a more compreh... | The study's primary limitation is that the SparseShape model relies on the quality of the input data from the mLocalCurv maps. The model's performance could be affected by the accuracy of the representations in the lower layers. The study acknowledges the potential for limitations in the RBO network, which is used to g... | "[{\"description\": \"SparseShape, a hierarchical model, effectively encodes signed curvature, distinguishing between convex and concave shapes, which is critical for accurate shape representation.\", \"supporting_evidence\": \"The model incorporates both curvature magnitude and sign, with the mEsSign cells computed us... | The study does not provide links to data or code. | The study includes a sparsity analysis to measure the number of parts contributing to mV4 responses in SparseShape. The model's performance was evaluated using a train/test split and cross-validation. | The study utilized electrophysiological responses of 109 Macaque V4 neurons, with data provided by Dr. Pasupathy. The study does not explicitly mention any ethical considerations or IRB approval. | Figure 4 illustrates the correlation coefficient distributions for different models. Figure 5 (a) demonstrates the sparsity distribution for the population. Figure 5 (b) shows the normalized sparse code vector distribution. Figure 5 (c) shows the distributions of facilitatory and inhibitory contributions. Figure 6 show... | (1) The core novel contribution is the development of SparseShape, a hierarchical model that explicitly encodes signed curvature and learns part-based selectivity, including both excitatory and inhibitory contributions, directly from Macaque V4 responses, which provides a more comprehensive understanding of V4 shape pr... | priv-gemini-2.0-flash-lite | 9,956 | 3,176 | https://openalex.org/W3197935448 | 10.1167/jov.21.9.1910 | Learning a model of shape selectivity in V4 cells reveals shape encoding mechanisms in the brain | article | 2,021 | 17 | en | false | true | [{"author": {"display_name": "Paria Mehrani", "id": "https://openalex.org/A5066048483", "orcid": "https://orcid.org/0000-0002-5566-9129"}, "affiliations": [{"institution_ids": ["https://openalex.org/I192455969"], "raw_affiliation_string": "York University"}], "countries": ["CA"], "raw_author_name": "Paria Mehrani", "is... | sanitized_title | true | 39,663 | Title: Learning a model of shape selectivity in V4 cells reveals shape encoding mechanisms in the brain
Authors: Paria Mehrani (York University); John K Tsotsos (York University)
Abstract:
The mechanisms involved in transforming early visual signals to curvature representations in V4 are unknown. We propose a hierarch... | Title: Learning a model of shape selectivity in V4 cells reveals shape encoding mechanisms in the brain
Authors: Paria Mehrani (York University); John K Tsotsos (York University)
Abstract:
The mechanisms involved in transforming early visual signals to curvature representations in V4 are unknown. We propose a hierarch... | Life Sciences | Neuroscience | Cognitive Neuroscience | Visual perception and processing mechanisms | 0.9982 | [{"id": "https://openalex.org/T10427", "display_name": "Visual perception and processing mechanisms", "score": 0.998199999332428, "subfield": {"id": "https://openalex.org/subfields/2805", "display_name": "Cognitive Neuroscience"}, "field": {"id": "https://openalex.org/fields/28", "display_name": "Neuroscience"}, "domai... | [] | ["Receptive field", "Computer science", "Macaque", "Curvature", "Stimulus (psychology)", "Neural coding", "Prior probability", "Gaussian", "Encoding (memory)", "Artificial intelligence", "Biological system", "Neuroscience", "Algorithm", "Pattern recognition (psychology)", "Physics", "Mathematics", "Bayesian probability... | gold | ||||
/mnt/sda/filtered tar files/arxiv-8-25/000000408_JSON.tar!000000408/output_0004059/0004059.json | arxiv-old | Chemotaxis in uncertain environments: hedging bets with multiple receptor types | "[{\"first\": \"Austin\", \"middle\": [], \"last\": \"Hopkins\", \"suffix\": \"\", \"affiliation\": (...TRUNCATED) | Chemotaxis in uncertain environments: hedging bets with multiple receptor types | Austin Hopkins (Johns Hopkins University); Brian A Camley (Johns Hopkins University) | Biology — Cell Biology | Theoretical | "This paper investigates how eukaryotic cells optimize chemotaxis in environments with varying chemi(...TRUNCATED) | "Eukaryotic cells chemotax by sensing chemical gradients via receptors on their surface. Prior work (...TRUNCATED) | "The central research question is: How do cells optimize chemotaxis in uncertain chemical environmen(...TRUNCATED) | "The study employs a theoretical modeling approach. The model generalizes the work of [5, 20], consi(...TRUNCATED) | "The study uses a mathematical model to analyze chemotaxis in uncertain environments. The model cons(...TRUNCATED) | "The study's key results are presented in figures and equations. Figure 1 shows the optimal fraction(...TRUNCATED) | "The findings suggest that cells adapt their receptor expression to the environmental uncertainty. T(...TRUNCATED) | "The study's main limitation is that the model does not consider the effects of receptor modificatio(...TRUNCATED) | "\"[{\\\"description\\\": \\\"Cells should express multiple receptor types with different affinities(...TRUNCATED) | "The study explores the robustness of the results by considering the effect of allowing the number o(...TRUNCATED) | "Figure 1 illustrates the optimal receptor fraction as a function of the typical concentration and e(...TRUNCATED) | "(1) The core novel contribution is the theoretical framework demonstrating that cells can improve c(...TRUNCATED) | priv-gemini-2.0-flash-lite | 10,542 | 2,943 | https://openalex.org/W3008749339 | 10.1103/physrevresearch.2.043146 | Chemotaxis in uncertain environments: Hedging bets with multiple receptor types | article | 2,020 | 10 | en | false | true | "[{\"author\": {\"display_name\": \"Austin Hopkins\"}, \"affiliations\": [{\"institution_ids\": [\"h(...TRUNCATED) | "[\"https://openalex.org/W246539152\", \"https://openalex.org/W960421816\", \"https://openalex.org/W(...TRUNCATED) | sanitized_title | true | 32,707 | "Title: Chemotaxis in uncertain environments: hedging bets with multiple receptor types\nAuthors: Au(...TRUNCATED) | "Title: Chemotaxis in uncertain environments: hedging bets with multiple receptor types\nAuthors: Au(...TRUNCATED) | Life Sciences | Biochemistry, Genetics and Molecular Biology | Cell Biology | Cellular Mechanics and Interactions | 0.5985 | "[{\"id\": \"https://openalex.org/T10379\", \"display_name\": \"Cellular Mechanics and Interactions\(...TRUNCATED) | [] | ["Chemotaxis", "Receptor", "Work (physics)", "Stability (learning theory)", "Cell type"] | gold | |||||
/mnt/sda/filtered tar files/arxiv-8-25/000000253_JSON.tar!000000253/output_0000388/0000388.json | arxiv-old | Puzzles in modern biology. III. Two kinds of causality in age-related disease | "[{\"first\": \"Steven\", \"middle\": [\"A\"], \"last\": \"Frank\", \"suffix\": \"\", \"affiliation\(...TRUNCATED) | Puzzles in modern biology. III. Two kinds of causality in age-related disease | Steven A Frank (University of California) | Biology — Aging | Theoretical | "This paper proposes a dual-causality framework for understanding age-related diseases, distinguishi(...TRUNCATED) | "The paper addresses the complexity of age-related diseases by proposing a framework that considers (...TRUNCATED) | "The central research question is how to understand the causal factors in age-related diseases. The (...TRUNCATED) | "The paper is a theoretical analysis and does not involve empirical experiments. The study design is(...TRUNCATED) | "This paper does not describe any specific procedures, architectures, or models. It presents a theor(...TRUNCATED) | "The paper presents a theoretical framework and does not report any empirical results. The main find(...TRUNCATED) | "The findings imply that a comprehensive understanding of age-related diseases requires considering (...TRUNCATED) | "The paper is a theoretical analysis and does not present any empirical data, which is a limitation.(...TRUNCATED) | "\"[{\\\"description\\\": \\\"Age-related diseases are caused by factors that influence both the rat(...TRUNCATED) | "The paper does not contain any figures or tables. The core claims are based on conceptual arguments(...TRUNCATED) | "(1) The core novel contribution is the dual-causality framework, which distinguishes between factor(...TRUNCATED) | priv-gemini-2.0-flash-lite | 2,922 | 2,166 | https://openalex.org/W2532719135 | 10.12688/f1000research.9789.2 | Puzzles in modern biology. III.Two kinds of causality in age-related disease | preprint | 2,017 | 1 | en | false | true | "[{\"author\": {\"display_name\": \"Steven A. Frank\", \"id\": \"https://openalex.org/A5056079279\",(...TRUNCATED) | "[\"https://openalex.org/W214964446\", \"https://openalex.org/W1650797637\", \"https://openalex.org/(...TRUNCATED) | sanitized_title | true | 5,892 | "Title: Puzzles in modern biology. III. Two kinds of causality in age-related disease\nAuthors: Stev(...TRUNCATED) | "Title: Puzzles in modern biology. III. Two kinds of causality in age-related disease\nAuthors: Stev(...TRUNCATED) | Life Sciences | Biochemistry, Genetics and Molecular Biology | Cell Biology | Microtubule and mitosis dynamics | 0.9947 | "[{\"id\": \"https://openalex.org/T10492\", \"display_name\": \"Microtubule and mitosis dynamics\", (...TRUNCATED) | [] | "[\"Disease\", \"Causality (physics)\", \"Physiology\", \"Function (biology)\", \"Cancer\", \"Biolog(...TRUNCATED) | gold | ||||||
/mnt/sda/filtered tar files/arxiv-8-25/000000253_JSON.tar!000000253/output_0003516/0003516.json | arxiv-old | Leaders and followers: Quantifying consistency in spatio-temporal propagation patterns | "[{\"first\": \"Thomas\", \"middle\": [], \"last\": \"Kreuz\", \"suffix\": \"\", \"affiliation\": {\(...TRUNCATED) | Leaders and followers: Quantifying consistency in spatio-temporal propagation patterns | Thomas Kreuz (CNR), Eero Satuvuori (CNR), Martin Pofahl (University of Bonn), Mario Mulansky (CNR) | Computational Neuroscience — Network Science | Methodological and Empirical | "This paper introduces a novel algorithm, built on two new measures, SPIKE-Order and Spike Train Ord(...TRUNCATED) | "The study addresses the need for methods to quantify spatio-temporal propagation patterns, which ar(...TRUNCATED) | "The central research question is how to quantify the consistency of leader-follower relationships i(...TRUNCATED) | "The study employed a methodological approach involving the development and application of a new alg(...TRUNCATED) | "The study introduces an algorithm built on two key measures: SPIKE-Order and Spike Train Order. Ada(...TRUNCATED) | "The study's key results are quantitative and span across different datasets. For artificially gener(...TRUNCATED) | "The findings support the use of SPIKE-Order and Spike Train Order in quantifying spatio-temporal pr(...TRUNCATED) | "The study acknowledges that the method deals purely with relative order and does not consider absol(...TRUNCATED) | "\"[{\\\"description\\\": \\\"The Synfire Indicator can quantify the consistency of leader-follower (...TRUNCATED) | "The algorithm is implemented in three publicly available software packages: SPIKY, cSPIKE, and PySp(...TRUNCATED) | "The study performed a background correction by setting a threshold value for the SPIKE-Synchronizat(...TRUNCATED) | "The study used data from mice brain slices. The study adhered to ethical considerations for the use(...TRUNCATED) | "Figure 1 illustrates the concept of synfire patterns and the sorting of spike trains. Figure 4 show(...TRUNCATED) | "(1) The core novel contribution is the introduction of the SPIKE-Order and Spike Train Order algori(...TRUNCATED) | priv-gemini-2.0-flash-lite | 15,404 | 3,141 | https://openalex.org/W2543392159 | 10.1088/1367-2630/aa68c3 | Leaders and followers: quantifying consistency in spatio-temporal propagation patterns | article | 2,017 | 24 | en | false | true | "[{\"author\": {\"display_name\": \"Thomas Kreuz\", \"orcid\": \"https://orcid.org/0000-0002-9213-82(...TRUNCATED) | "[\"https://openalex.org/W64751957\", \"https://openalex.org/W1517195678\", \"https://openalex.org/W(...TRUNCATED) | sanitized_title | true | 60,646 | "Title: Leaders and followers: Quantifying consistency in spatio-temporal propagation patterns\nAuth(...TRUNCATED) | "Title: Leaders and followers: Quantifying consistency in spatio-temporal propagation patterns\nAuth(...TRUNCATED) | Life Sciences | Neuroscience | Cognitive Neuroscience | Neural dynamics and brain function | 0.6979 | "[{\"id\": \"https://openalex.org/T10581\", \"display_name\": \"Neural dynamics and brain function\"(...TRUNCATED) | [] | "[\"Spike (software development)\", \"Consistency (knowledge bases)\", \"Flexibility (engineering)\"(...TRUNCATED) | gold | |||
"/mnt/sdb/filtered tar files/arxiv-8-25/pdfs_000110_JSON.tar!minio-pdfs/output_PMC3648493_1471-2407-(...TRUNCATED) | arxiv-old | "VEGF is an important mediator of tumor angiogenesis in malignant lesions in a genetically engineere(...TRUNCATED) | "[{\"first\": \"Bharat\", \"middle\": [\"K\"], \"last\": \"Majeti\", \"suffix\": \"\", \"affiliation(...TRUNCATED) | "VEGF is an important mediator of tumor angiogenesis in malignant lesions in a genetically engineere(...TRUNCATED) | Bharat K Majeti, Joseph H Lee, Brett H Simmons, Farbod Shojaei | Oncology — Angiogenesis | Empirical | "This study investigated the efficacy of vascular endothelial growth factor (VEGF) inhibitors in a g(...TRUNCATED) | "Angiogenesis, the formation of new blood vessels, is crucial for tumor growth and progression. VEGF(...TRUNCATED) | "The central research question is whether VEGF inhibitors can effectively suppress lung tumor growth(...TRUNCATED) | "The study used a Kras G12D-LSL GEMM to investigate the efficacy of VEGF inhibitors. Kras G12D-LSL h(...TRUNCATED) | "The study utilized a Kras G12D-LSL GEMM to investigate the effects of VEGF inhibitors. The GEMM was(...TRUNCATED) | "The study found that all three VEGF inhibitors significantly reduced the percentage of malignant (a(...TRUNCATED) | "The findings support the hypothesis that VEGF is a key regulator of tumor angiogenesis in the Kras (...TRUNCATED) | "A key limitation is that the study did not investigate the pharmacokinetics and pharmacodynamics of(...TRUNCATED) | "\"[{\\\"description\\\": \\\"VEGF inhibitors significantly reduce the percentage of malignant (aden(...TRUNCATED) | "The study was conducted under the guidelines provided by IACUC. All animal study procedures were mo(...TRUNCATED) | "Figure 3A shows the percentage of each type of lesion in the recipient lung. It demonstrates that t(...TRUNCATED) | "(1) The core novel contribution is the demonstration that VEGF inhibitors effectively suppress the (...TRUNCATED) | priv-gemini-2.0-flash-lite | 5,848 | 2,784 | https://openalex.org/W2046450429 | 10.1186/1471-2407-13-213 | "VEGF is an important mediator of tumor angiogenesis in malignant lesions in a genetically engineere(...TRUNCATED) | article | 2,013 | 33 | en | false | true | "[{\"author\": {\"display_name\": \"Bharat K. Majeti\", \"id\": \"https://openalex.org/A5051881221\"(...TRUNCATED) | "[\"https://openalex.org/W164619530\", \"https://openalex.org/W1571559303\", \"https://openalex.org/(...TRUNCATED) | sanitized_title | true | 18,182 | "Title: VEGF is an important mediator of tumor angiogenesis in malignant lesions in a genetically en(...TRUNCATED) | "Title: VEGF is an important mediator of tumor angiogenesis in malignant lesions in a genetically en(...TRUNCATED) | Life Sciences | Biochemistry, Genetics and Molecular Biology | Molecular Biology | Angiogenesis and VEGF in Cancer | 0.7851 | "[{\"id\": \"https://openalex.org/T10422\", \"display_name\": \"Angiogenesis and VEGF in Cancer\", \(...TRUNCATED) | "[{\"descriptor_ui\": \"D000230\", \"descriptor_name\": \"Adenocarcinoma\", \"qualifier_ui\": \"Q000(...TRUNCATED) | "[\"Angiogenesis\", \"Atypical adenomatous hyperplasia\", \"Carcinogenesis\", \"Cancer research\", \(...TRUNCATED) | gold | |||||
"/mnt/sdb/filtered tar files/arxiv-8-25/pdfs_000110_JSON.tar!minio-pdfs/output_JDB-14-394/JDB-14-394(...TRUNCATED) | arxiv-old | Effect of type 2 diabetes on A disintegrin and metalloprotease 10 | "[{\"first\": \"Sum\", \"middle\": [], \"last\": \"Lam\", \"suffix\": \"\", \"affiliation\": {}, \"e(...TRUNCATED) | Effect of type 2 diabetes on A disintegrin and metalloprotease 10 | "Sum Lam; Sammy Wing; Ming Shiu; Ying Wong; | Kathryn; Choon-Beng Tan; Kathryn Tan; Kathryn Choon-Be(...TRUNCATED) | Endocrinology — Diabetes | Empirical | "This study investigated the impact of type 2 diabetes on serum levels of A disintegrin and metallop(...TRUNCATED) | "ADAM10 is a transmembrane protein responsible for cleaving various cell surface molecules and has b(...TRUNCATED) | "The central research question was whether type 2 diabetes is associated with changes in serum ADAM1(...TRUNCATED) | "The study employed a cross-sectional design. A total of 1091 individuals with type 2 diabetes and 3(...TRUNCATED) | "The study utilized commercially available ELISA kits (R&D systems, Minneapolis, Minnesota) to measu(...TRUNCATED) | "Serum ADAM10 levels were significantly higher in individuals with diabetes compared to controls (40(...TRUNCATED) | "The findings suggest that elevated serum ADAM10 levels in type 2 diabetes are associated with glyce(...TRUNCATED) | "The study's cross-sectional design limits the ability to establish causal relationships between dia(...TRUNCATED) | "\"[{\\\"description\\\": \\\"Serum ADAM10 levels are significantly higher in individuals with type (...TRUNCATED) | "The study was approved by the ethics committee of the University of Hong Kong and conformed to the (...TRUNCATED) | "Table 1 presents the clinical characteristics of the study participants, showing the differences in(...TRUNCATED) | "(1) The core novel contribution is the demonstration that serum ADAM10 levels are significantly ele(...TRUNCATED) | priv-gemini-2.0-flash-lite | 5,797 | 3,150 | https://openalex.org/W4282965608 | 10.1111/1753-0407.13287 | Effect of type 2 diabetes on A disintegrin and metalloprotease 10 | article | 2,022 | 12 | en | false | true | "[{\"author\": {\"display_name\": \"Sum Lam\", \"id\": \"https://openalex.org/A5102051780\"}, \"affi(...TRUNCATED) | "[\"https://openalex.org/W1488696728\", \"https://openalex.org/W1908100791\", \"https://openalex.org(...TRUNCATED) | sanitized_title | true | 17,279 | "Title: Effect of type 2 diabetes on A disintegrin and metalloprotease 10\nAuthors: Sum Lam; Sammy W(...TRUNCATED) | "Title: Effect of type 2 diabetes on A disintegrin and metalloprotease 10\nAuthors: Sum Lam; Sammy W(...TRUNCATED) | Life Sciences | Immunology and Microbiology | Immunology | Atherosclerosis and Cardiovascular Diseases | 0.9282 | "[{\"id\": \"https://openalex.org/T12955\", \"display_name\": \"Atherosclerosis and Cardiovascular D(...TRUNCATED) | "[{\"descriptor_ui\": \"D003924\", \"descriptor_name\": \"Diabetes Mellitus, Type 2\", \"qualifier_u(...TRUNCATED) | "[\"ADAM10\", \"Metalloproteinase\", \"Diabetes mellitus\", \"Endocrinology\", \"Internal medicine\"(...TRUNCATED) | gold | |||||
"/mnt/sdb/filtered tar files/arxiv-8-25/pdfs_000110_JSON.tar!minio-pdfs/output_PMC3605849_ece30003-0(...TRUNCATED) | arxiv-old | Geographically multifarious phenotypic divergence during speciation | "[{\"first\": \"Zachariah\", \"middle\": [], \"last\": \"Gompert\", \"suffix\": \"\", \"affiliation\(...TRUNCATED) | Geographically multifarious phenotypic divergence during speciation | "Zachariah Gompert (University of Wyoming), Lauren K Lucas (Texas State University), Chris C Nice (T(...TRUNCATED) | Evolutionary Biology — Speciation | Empirical | "This study investigates phenotypic divergence and potential barriers to gene flow between the butte(...TRUNCATED) | "Speciation, the formation of new species, often involves the evolution of barriers to gene flow, wh(...TRUNCATED) | "The central research questions are: (1) Does phenotypic divergence between *L. idas* and *L. meliss(...TRUNCATED) | "The study employed a combination of field and laboratory experiments to investigate phenotypic dive(...TRUNCATED) | "The study involved several experimental procedures and analyses. For oviposition preference experim(...TRUNCATED) | "The study found that *L. idas* and *L. melissa* exhibit divergence across multiple phenotypic axes.(...TRUNCATED) | "The findings suggest that *L. idas* and *L. melissa* are diverging along multiple phenotypic axes, (...TRUNCATED) | "The study's findings are consistent with the hypothesis that multiple phenotypic traits contribute (...TRUNCATED) | "\"[{\\\"description\\\": \\\"The butterfly species *L. idas* and *L. melissa* exhibit phenotypic di(...TRUNCATED) | "All necessary permits were obtained for the described field studies (USA National Park research per(...TRUNCATED) | "Figure 2 shows the oviposition preference of different populations. Figure 4 shows the male mate pr(...TRUNCATED) | "(1) The study demonstrates that *L. idas* and *L. melissa* have diverged along multiple phenotypic (...TRUNCATED) | priv-gemini-2.0-flash-lite | 14,922 | 3,536 | https://openalex.org/W2043806930 | 10.1002/ece3.445 | Geographically multifarious phenotypic divergence during speciation | article | 2,013 | 23 | en | false | true | "[{\"author\": {\"display_name\": \"Zachariah Gompert\", \"id\": \"https://openalex.org/A5030626361\(...TRUNCATED) | "[\"https://openalex.org/W129150789\", \"https://openalex.org/W150224778\", \"https://openalex.org/W(...TRUNCATED) | sanitized_title | true | 59,329 | "Title: Geographically multifarious phenotypic divergence during speciation\nAuthors: Zachariah Gomp(...TRUNCATED) | "Title: Geographically multifarious phenotypic divergence during speciation\nAuthors: Zachariah Gomp(...TRUNCATED) | Life Sciences | Agricultural and Biological Sciences | Ecology, Evolution, Behavior and Systematics | Plant and animal studies | 0.9999 | "[{\"id\": \"https://openalex.org/T10487\", \"display_name\": \"Plant and animal studies\", \"score\(...TRUNCATED) | [] | "[\"Biology\", \"Gene flow\", \"Genetic algorithm\", \"Phenotypic trait\", \"Evolutionary biology\",(...TRUNCATED) | gold | |||||
"/mnt/sdb/filtered tar files/arxiv-8-25/pdfs_000110_JSON.tar!minio-pdfs/output_PMC2727780_btt-2-161/(...TRUNCATED) | arxiv-old | The potential role of curcumin (diferuloylmethane) in plasma cell dyscrasias/ paraproteinemia | "[{\"first\": \"Terry\", \"middle\": [], \"last\": \"Golombick\", \"suffix\": \"\", \"affiliation\":(...TRUNCATED) | The potential role of curcumin (diferuloylmethane) in plasma cell dyscrasias/ paraproteinemia | Terry Golombick, Terry Diamond | Medicine — Oncology | Empirical | "This pilot study investigates the potential of curcumin, a compound derived from turmeric, in treat(...TRUNCATED) | "Plasma cell dyscrasias, including MGUS, are characterized by paraproteinemia, where no current trea(...TRUNCATED) | "The central research question is whether curcumin can reduce serum paraprotein levels in patients w(...TRUNCATED) | "The study employed a single-blind, randomized, controlled pilot study design. The study enrolled 25(...TRUNCATED) | "The study involved a single-blind, randomized, controlled pilot study. The study included 25 patien(...TRUNCATED) | "The study reported a drop of between 5% and 30% serum paraprotein in some patients taking curcumin (...TRUNCATED) | "The preliminary findings suggest that curcumin may have a role in reducing paraprotein levels in pa(...TRUNCATED) | "The study's primary limitation is the small sample size (N=25), which limits the statistical power (...TRUNCATED) | "\"[{\\\"description\\\": \\\"Curcumin administration resulted in a reduction of serum paraprotein l(...TRUNCATED) | "The study mentions figures, but they are not included in the provided text. The figures likely show(...TRUNCATED) | "(1) The core novel contribution is the preliminary evidence suggesting that curcumin can reduce ser(...TRUNCATED) | priv-gemini-2.0-flash-lite | 3,469 | 2,322 | https://openalex.org/W1972768342 | 10.2147/btt.s2514 | The potential role of curcumin (diferuloylmethane) in plasma cell dyscrasias/paraproteinemia | article | 2,008 | 7 | en | false | true | "[{\"author\": {\"display_name\": \"Terry Golombick\", \"id\": \"https://openalex.org/A5028828747\",(...TRUNCATED) | "[\"https://openalex.org/W1994722812\", \"https://openalex.org/W2091774785\", \"https://openalex.org(...TRUNCATED) | sanitized_title | true | 7,585 | "Title: The potential role of curcumin (diferuloylmethane) in plasma cell dyscrasias/ paraproteinemi(...TRUNCATED) | "Title: The potential role of curcumin (diferuloylmethane) in plasma cell dyscrasias/ paraproteinemi(...TRUNCATED) | Life Sciences | Biochemistry, Genetics and Molecular Biology | Molecular Medicine | Curcumin's Biomedical Applications | 0.9994 | "[{\"id\": \"https://openalex.org/T11319\", \"display_name\": \"Curcumin's Biomedical Applications\"(...TRUNCATED) | [] | "[\"Paraproteinemia\", \"Dyscrasia\", \"Multiple myeloma\", \"Plasma cell\", \"Monoclonal gammopathy(...TRUNCATED) | gold | ||||||
"/mnt/sdb/filtered tar files/arxiv-8-25/pdfs_000110_JSON.tar!minio-pdfs/output_PMC11320351_ACEL-23-e(...TRUNCATED) | arxiv-old | "Unveiling ceramide dynamics: Shedding light on healthy aging in growth hormone-releasing hormone kn(...TRUNCATED) | "[{\"first\": \"Alexander\", \"middle\": [\"Tate\"], \"last\": \"Lasher\", \"suffix\": \"\", \"affil(...TRUNCATED) | "Unveiling ceramide dynamics: Shedding light on healthy aging in growth hormone-releasing hormone kn(...TRUNCATED) | "Alexander Tate Lasher (University of Alabama at Birmingham); Liping Wang (University of Utah); Jooy(...TRUNCATED) | Biology — Aging | Empirical | "This study investigated the role of ceramide metabolism in the extended lifespan of growth hormone-(...TRUNCATED) | "The study addresses the need to understand the molecular mechanisms underlying the extended lifespa(...TRUNCATED) | "The central research question is whether ceramide metabolism is altered in GHRH-KO mice and if this(...TRUNCATED) | "The study employed a targeted lipidomic analysis to assess sphingolipid and related lipid concentra(...TRUNCATED) | "The study involved the following procedures: (1) Serum and liver tissue collection from GHRH-KO and(...TRUNCATED) | "The study found no discernable differences in serum lipids between younger (3-5 months) GHRH-KO and(...TRUNCATED) | "The findings suggest that altered ceramide metabolism is associated with the extended lifespan of G(...TRUNCATED) | "The study's primary limitation is the focus on female mice, which limits the generalizability of th(...TRUNCATED) | "\"[{\\\"description\\\": \\\"Older (10–15 months) GHRH-KO mice exhibit a distinct grouping in ser(...TRUNCATED) | "Figure 1a shows the principal component analysis (PCA) of serum lipid profiles, demonstrating a sep(...TRUNCATED) | "(1) The core novel contribution is the first demonstration that sphingolipid metabolism, specifical(...TRUNCATED) | priv-gemini-2.0-flash-lite | 4,316 | 2,664 | https://openalex.org/W4399125924 | 10.1111/acel.14226 | "Unveiling ceramide dynamics: Shedding light on healthy aging in growth hormone‐releasing hormone (...TRUNCATED) | article | 2,024 | 3 | en | false | true | "[{\"author\": {\"display_name\": \"Alexander Tate Lasher\", \"id\": \"https://openalex.org/A5017944(...TRUNCATED) | "[\"https://openalex.org/W1850582709\", \"https://openalex.org/W1967083598\", \"https://openalex.org(...TRUNCATED) | sanitized_title | true | 10,945 | "Title: Unveiling ceramide dynamics: Shedding light on healthy aging in growth hormone-releasing hor(...TRUNCATED) | "Title: Unveiling ceramide dynamics: Shedding light on healthy aging in growth hormone-releasing hor(...TRUNCATED) | Life Sciences | Biochemistry, Genetics and Molecular Biology | Molecular Biology | Sphingolipid Metabolism and Signaling | 0.996 | "[{\"id\": \"https://openalex.org/T11308\", \"display_name\": \"Sphingolipid Metabolism and Signalin(...TRUNCATED) | "[{\"descriptor_ui\": \"D000375\", \"descriptor_name\": \"Aging\", \"qualifier_ui\": \"Q000378\", \"(...TRUNCATED) | "[\"Ceramide\", \"Biology\", \"Endocrinology\", \"Hormone\", \"Internal medicine\", \"Knockout mouse(...TRUNCATED) | gold | ||||||
"/mnt/sdb/filtered tar files/arxiv-8-25/pdfs_000110_JSON.tar!minio-pdfs/output_PMC3744010_fnins-07-0(...TRUNCATED) | arxiv-old | Mechanism based approaches for rescuing and enhancing cognition | "[{\"first\": \"Gary\", \"middle\": [], \"last\": \"Lynch\", \"suffix\": \"\", \"affiliation\": {\"l(...TRUNCATED) | Mechanism based approaches for rescuing and enhancing cognition | Gary Lynch (University of California); Christine M Gall (University of California) | Neuroscience — Neuropharmacology | Review | "This review explores mechanism-based approaches for cognitive enhancement, focusing on the neurobio(...TRUNCATED) | "The field of cognitive enhancement is motivated by the need to address intellectual impairments ass(...TRUNCATED) | "The central research questions revolve around the mechanisms of memory encoding, the potential for (...TRUNCATED) | "The review paper synthesizes findings from various studies, primarily focusing on rodent models. Th(...TRUNCATED) | "The review focuses on the neurobiological mechanisms underlying memory encoding, specifically long-(...TRUNCATED) | "The review presents several key results related to the mechanisms of LTP and the effects of ampakin(...TRUNCATED) | "The findings suggest that the cytoskeletal machinery involved in LTP consolidation is a common targ(...TRUNCATED) | "The review acknowledges several limitations and contradictions. The review does not provide detaile(...TRUNCATED) | "\"[{\\\"description\\\": \\\"Impairments in the cytoskeletal machinery that stabilizes memory repre(...TRUNCATED) | "The review paper does not provide links to data or code. No information is provided about licenses (...TRUNCATED) | "The review does not provide specific details about robustness or ablation analyses. However, the re(...TRUNCATED) | "The review does not explicitly mention ethical considerations, risks, mitigations, or approvals. Th(...TRUNCATED) | "Figure 2 illustrates the characteristics of long-term potentiation (LTP), showing the synapse speci(...TRUNCATED) | "(1) The core novel contribution is the proposed mechanism-based approach for cognitive enhancement,(...TRUNCATED) | priv-gemini-2.0-flash-lite | 12,734 | 3,672 | https://openalex.org/W4250312368 | 10.3389/fnins.2013.00101 | Mechanism based approaches for rescuing and enhancing cognition | article | 2,013 | 2 | en | false | true | "[{\"author\": {\"display_name\": \"Gary Lynch\", \"id\": \"https://openalex.org/A5074348666\", \"or(...TRUNCATED) | "[\"https://openalex.org/W44985057\", \"https://openalex.org/W66447799\", \"https://openalex.org/W19(...TRUNCATED) | sanitized_title | true | 53,020 | "Title: Mechanism based approaches for rescuing and enhancing cognition\nAuthors: Gary Lynch (Univer(...TRUNCATED) | "Title: Mechanism based approaches for rescuing and enhancing cognition\nAuthors: Gary Lynch (Univer(...TRUNCATED) | Life Sciences | Neuroscience | Cellular and Molecular Neuroscience | Neuroscience and Neuropharmacology Research | 0.9995 | "[{\"id\": \"https://openalex.org/T10077\", \"display_name\": \"Neuroscience and Neuropharmacology R(...TRUNCATED) | [] | "[\"Mechanism (biology)\", \"Cognition\", \"Computer science\", \"Neuroscience\", \"Cognitive scienc(...TRUNCATED) | gold |
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